前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白
Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9
- 編號RPE189Ra01
- 物種Rattus norvegicus (Rat,大鼠) 相同的名稱,不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌, 溶酶體, 細(xì)胞質(zhì), 高爾基體, 內(nèi)質(zhì)網(wǎng)腔, 內(nèi)體
- 預(yù)測分子量58.1kDa
- 實(shí)際分子量58kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Trp164~Phe428 with N-terminal His and GST Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)5.9
-
應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 1195 ¥ 2988 ¥ 5976 ¥ 17928 ¥ 44820
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序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月,-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
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編號 | 適用物種:Rattus norvegicus (Rat,大鼠) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)多克隆抗體 | WB; IHC; ICC; IP. |
MAE189Ra23 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC; ICC; IP. |
MAE189Ra22 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC; ICC; IP. |
MAE189Ra21 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC |
SEE189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LME189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
Biological Trace Element Research | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers [pubmed:28409410] |
BASIC RESEARCH IN CARDIOLOGY | Autocrine effects of PCSK9 on cardiomyocytes [Pubmed: 33169229] |
J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans [33407555] |
Metabolism | MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice [33775647] |
Eur Rev Med Pharmacol Sci | Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders [34533801] |
Clin Exp Hypertens | Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease [Pubmed:35502687] |
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