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不對稱二甲基精氨酸(ADMA)多克隆抗體

Polyclonal Antibody to Asymmetrical Dimethylarginine (ADMA)

N,N-Dimethylarginine; NG,NG-Dimethylarginine dihydrochloride; Asymmetric Dimethylarginine

  • 不對稱二甲基精氨酸(ADMA)多克隆抗體 產(chǎn)品包裝(模擬)
  • 不對稱二甲基精氨酸(ADMA)多克隆抗體 產(chǎn)品包裝(模擬)
  • Certificate 通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

The antibody is a rabbit polyclonal antibody raised against ADMA. It has been selected for its ability to recognize ADMA in ELISA and CLIA.

用法

Enzyme-Linked Immune Sorbent Assay: 200ng/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

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參考文獻(xiàn)

雜志 參考文獻(xiàn)
PLoS One. Interactions among Vascular-Tone Modulators Contribute to High Altitude Pulmonary Edema and Augmented Vasoreactivity in Highlanders [PubMed: PMC3439466]
Cytokine Effect of CCL5 on dimethylarginine dimethylaminohydrolase-1 production in vascular smooth muscle cells from spontaneously hypertensive rats. [Pubmed: 23834755]
Neurol Res. Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats. [Pubmed:25475507]
Int J Clin Exp Med. Correlation research on ADMA plasma levels and left ventricular function of peritoneal dialysis patients [Pubmed:25550968]
Clin Respir J Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD [PubMed: 26076870]
Cytokine Dimethylarginine dimethylaminohydrolase-1 mediates inhibitory effect of interleukin-10 on angiotensin II-induced hypertensive effects in vascular smooth muscle cells of spontaneously hypertensive rats [PubMed: 26375520]
Neurological Research Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats [PubMed: 25475507]
Scientific Reports Dimethylarginine Dimethylaminohydrolase 2 (DDAH 2) Gene Polymorphism, Asymmetric Dimethylarginine (ADMA) Concentrations, and Risk of Coronary Artery Disease: A Case-Control Study [pubmed:27677852]
clinica chimica acta Increased serum concentrations of asymmetric dimethylarginine (ADMA) in patients with early-onset coronary artery disease. [pubmed:27884754]
The?Journal?of?Physiology Asymmetric?dimethylarginine?(ADMA)?elevation?and?arginase?up-regulation?contribute?toendothelial?dysfunction?related?to?insulin?resistance?in?rats?and morbidly obese humans. [pubmed:26840628]
Angiogenesis Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA). [pubmed:29150732]
Scientific Reports A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling [Pubmed:29523851]
Mechanisms of?Ageing?and Development Multivessel analysis of progressive vascular aging in the rat: Asynchronous vulnerability among vascular territories [Pubmed:29605639]
Nutrition, Metabolism and Cardiovascular Diseases Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns [Doi: 10.1016/j.numecd.2018.09.002]
Biochemical?and?Biophysical?Research?Communications Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1/DDAH/PPAR-γ/eNOS pathways in streptozotocin-induced diabetic rats [Pubmed: 30454888]
Brazilian?Journal?of?Pharmaceutical?Science Demographic, clinical and lifestyle predictors for severity of erectile dysfunction and biomarkers level in Malaysian patients []
ACS?Combinatorial?Science Novel cellularly active inhibitor regresses DDAH1 induced prostate tumor growth by restraining tumor angiogenesis through targeting DDAH1/ADMA/NOS pathway [Pubmed: 30673277]
International Journal of the Cardiovascular Academy Nebivolol prevents the increase of asymmetric dimethylarginine and oxidants in hyperhomocysteinemic rats []
Oxid Med Cell Longev The Role of Reactive Oxygen Species and Nitric Oxide in the Inhibition of Trichophyton rubrum Growth by HaCaT Cells [Pubmed: 32104540]
Molecular Medicine Reports Blueberry anthocyanin?enriched extract ameliorates transverse aortic constriction?induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in?… [Pubmed: 31746378]
International Journal of Nephrology Effect of a Supervised Peridialytic Exercise Program on Serum Asymmetric Dimethylarginine in Maintenance Hemodialysis Patients [Pubmed: 33163233]
Journal of Clinical Medicine The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial [Pubmed: 32344735]
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Levels of endothelial substances in patients with newly identified hypertension compared with healthy controls [33463628]
WIENER KLINISCHE WOCHENSCHRIFT Non-functioning adrenal incidentalomas may increase toxic metabolites [34255169]
pharmaceuticals Effect of a Low Dose of Carvedilol on Cyclophosphamide-Induced Urinary Toxicity in Rats—A Comparison with Mesna [34959638]
Int J Biochem Cell Biol HIF-1α and Nrf2 regulates hypoxia induced overexpression of DDAH1 through promoter activation in prostate cancer [Pubmed:35644470]
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