Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體
Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI)
CTX-I; CTX1;
- 編號MAA665Mi27
- 物種Homo sapiens (Human,人), Canis familiaris; Canine (Dog,犬), Bos taurus; Bovine (Cattle,牛), Chicken (Gallus,雞) 相同的名稱,不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)E8
- Ig亞型 N/A
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 -
- 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性狀液體
- 濃度1mg/ml
- 且適物種-
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術,請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 619 ¥ 1445 ¥ 2064 ¥ 5160 ¥ 20640
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特異性
該抗體是針對CTXI的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別CTXI。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunofluorescence:5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質期內,在適當?shù)臈l件下存儲,損失率低于5%。
贈品
相關產(chǎn)品
編號 | 適用物種:Homo sapiens (Human,人), Canis familiaris; Canine (Dog,犬), Bos taurus; Bovine (Cattle,牛), Chicken (Gallus,雞) | 應用(僅供研究使用,不用于臨床診斷!) |
MAA665Mi21 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi28 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi26 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi27 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi22 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi23 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi24 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
MAA665Mi25 | Ⅰ型膠原交聯(lián)羧基端肽(CTXI)單克隆抗體 | WB; IHC; ICC; IP. |
參考文獻
雜志 | 參考文獻 |
journal of bone and mineral research | Atp6v0d2 Is an Essential Component of the Osteoclast-Specific Proton Pump That Mediates Extracellular Acidification in Bone Resorption [PubMed: PMC2672205] |
Bone | Borage and fish oils lifelong supplementation decreases inflammation and improves bone health in a murine model of senile osteoporosis [PubMed: 21664309] |
Trials | Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial. [Trials: 1745-6215] |
Journal of Biological Chemistry | TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation [PubMed: 22773835] |
The Journal of Clinical Endocrinology & Metabolism | A Mediterranean Diet Enriched with Olive Oil Is Associated with Higher Serum Total Osteocalcin Levels in Elderly Men at High Cardiovascular Risk [PubMed: PMC3462931] |
Endocrinology | Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain [Endocrine: Source] |
Am J Physiol Endocrinol Metab. | DPP IV inhibitor treatment attenuates bone loss and improves mechanical bone strength in male diabetic rats [Pubmed:25053403] |
The American Journal of Cardiology | Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease [Pubmed:25073565] |
Rheumatology (Oxford). | Bone resorption correlates with the frequency of CD5+ B cells in the blood of patients with rheumatoid arthritis [Pubmed:25193807] |
XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa) [Pubmed:25284315] | |
Rheumatology International | The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis [Pubmed:25630523] |
The Journal of Biological Chemistry | 5-azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival [Pubmed:25691576] |
Scandinavian Journal of Clinical and Laboratory Investigation | Osteocartilaginous metabolic markers change over a 3-week stage race in pro-cyclists [PubMed: 26174975] |
AIDS | Effects of renal tubular dysfunction on bone in tenofovir-exposed HIV-positive patients [PubMed: 26372384] |
the journal of rheumatology | Biomarkers in Remission According to Different Criteria in Patients with Rheumatoid Arthritis [PubMed: 26472417] |
Int J Mol Med | Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway [PubMed: 26677102] |
the journal of biological chemistry | Mutation in Osteoactivin Promotes RANKL-Mediated Osteoclast Differentiation and Survival, but Inhibits Osteoclast Function [PubMed: 25837253] |
frontiers in endocrinology | Oxytocin reverses osteoporosis in a sex-dependent manner [PubMed: 26042090] |
PLoS One.? | The RIP1–RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats [pmc:PMC4795547] |
J Cell Physiol | Lanthanum Chloride Attenuates Osteoclast Formation and Function Via the DownreCavia (Guinea pig )lation of Rankl-Induced Nf-κb and Nfatc1 Activities [Pubmed:26060084] |
FASEB Journal | N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities. [pubmed:27530978] |
Metabolism. | High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients. [pubmed:28521869] |
journal of science and medicine in sport | The effect of calcium and vitamin D supplementation on bone health of male Jockeys. [pubmed:27568072] |
Chemico-Biological Interactions | Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway [pubmed:27387537] |
Epilepsy?Research | The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats [pubmed:27838501] |
Bone | Reduced femoral bone mass in both diet-induced and genetic hyperlipidemia mice [pubmed:27669658] |
Journal?of?Vascular?Surgery | A?potential?role?for?glycated?cross-links?in?abdominal?aortic?aneurysm?disease. [pubmed:27624703] |
Institute?of?Pharmacology | Effects?of?long-term?administration?of?pantoprazole?on?bone?mineral?density?in?young?male?rats. [pubmed:27552060] |
Biomedicine & Pharmacotherapy | Anti-osteoporotic effects of an antidepressant tianeptine on ovariectomized rats [S0753332216322752] |
European Journal of Pharmacology | Cannabidiol administration reduces sublesional cancellous bone loss in rats with severe spinal cord injury [pubmed:28479140] |
APPLIED?SPECTROSCOPY | Side-Effects of Convulsive Seizures and Anti-Seizure Therapy on Bone in a Rat Model of Epilepsy [pubmed:28905646] |
Clinical Nutrition | Obesity status influences the relationship among serum osteocalcin, iron stores and insulin sensitivity [pubmed:29050649] |
Oncotarget | A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice. [pubmed:28060768] |
中國骨質疏松雜志 | 骨形成指標PINP 與骨吸收指標β-CTX 在2 型糖尿病合并骨質疏松中作用的研究. [10.3969/j.issn.1006-7108.2017.03.009] |
BioMed Research International | Optimization of the Time Window of Interest in Ovariectomized Imprinting Control Region Mice for Antiosteoporosis Research [pubmed:29119115] |
Cell?Death?And Differentiation | TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42 [Pubmed:29358671] |
Journal of Periodontology? | The role of androgens on periodontal repair in female rats [Pubmed:29683499] |
Life?Sciences | Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway [Pubmed:29883721] |
European?Journal of Pharmacology | The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism [Pubmed:29428468] |
Journal of Clinical Densitometry | Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX study [Pubmed:30076009] |
Pharmacology | Effects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive Rats [Pubmed:29898457] |
Experimental and Therapeutic Medicine | Liraglutide exerts a bone?protective effect in ovariectomized rats with streptozotocin?induced diabetes by inhibiting osteoclastogenesis [Pubmed:29805533] |
Experimental and Therapeutic Medicine | Combination therapy with BMP?2 and psoralen enhances fracture healing in ovariectomized mice [10.3892:etm.2018.6353] |
Tumor Biology | Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling [Pubmed:29687745] |
Sensors | Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers [Pubmed: 30181433] |
Tropical Journal of Pharmaceutical Research | Mollugin attenuates glucocorticoid-induced osteoporosis in rats via Akt/P13K pathway [] |
Bone?&?Joint?Research | Transcriptome analysis of osteoblasts in an ovariectomized mouse model in response to physical exercise [] |
Toxicol Ind Health | Influence of physical training on markers of bone turnover, mechanical properties, morphological alterations, density and mineral contents in the femur of rats exposed?… [Pubmed: 30983556] |
Journal of Geriatric?Oncology | Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors [Pubmed: 30952517] |
Scientific?Reports | Significance of the Tks4 scaffold protein in bone tissue homeostasis [] |
E The Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats [] | |
Biology Open | Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice [Pubmed: 31088250] |
Journal of Periodontology | Role of testosterone and androgen receptor in periodontal disease progression in female rats [Pubmed: 31389012] |
Journal of clinical periodontology | Biomarkers of oral inflammation in perinatally HIV‐infected and perinatally HIV exposed, uninfected youth [Pubmed: 31385616] |
Bulletin of Experimental Biology and Medicine | Laboratory Monitoring of Bone Tissue Remodeling after Augmentation of Impression Intraarticular Fracture with Different Types of Bone Graft [Pubmed: 31630302] |
Molecular Therapy-Nucleic Acids | AAV-anti-miR-214 prevents collapse of the femoral head in osteonecrosis by regulating osteoblast and osteoclast activities [Pubmed: 31739209] |
International Journal of Environmental Research and Public Health | Alleviating Effect of α-Lipoic Acid and Magnesium on Cadmium-Induced Inflammatory Processes, Oxidative Stress and Bone Metabolism Disorders in Wistar Rats [Pubmed: 31739465] |
International journal of molecular sciences | Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients [Pubmed: 31717649] |
Brazilian Journal of Medical and Biological Research | Beneficial effects of Cuscuta chinensis extract on glucocorticoid-induced osteoporosis through modulation of RANKL/OPG signals [Pubmed: 31826180] |
Journal of Bone and Mineral Research | BMP9 reduces bone loss in ovariectomized mice by dual regulation of bone remodeling [Pubmed: 31914211] |
Theranostics | EDTA-Modified 17β-Estradiol-Laden Upconversion Nanocomposite for Bone-Targeted Hormone Replacement Therapy for Osteoporosis [Pubmed: 32194868] |
Cells | Article Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous?… [Pubmed: 31877673] |
Cell | RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis [Pubmed: 32640190] |
Advanced Science | A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype … [Pubmed: 32670749] |
International Medical Journal Malaysia | The Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats. [] |
Cells. | Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous?… [] |
Journal of Orthopaedic Translation | Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomized rats [] |
Research square | 4-Hexylresorcinol Inhibits Osteoclastogenesis by Suppressing NF‐κB Signaling Pathway and Reverses Bone Loss in Ovariectomized Mice [] |
IIUM Medical Journal Malaysia | The Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats [] |
淫羊藿水提物及提取藥渣的抗骨質疏松藥效比較研究 [] | |
Pamukkale T?p Dergisi | Postmenapozal Tip-2 diyabetes mellitus' lu hastalarda osteoporoza ba?l? k?r?k riskinin ve kemik Turnoveri'nin de?erlendirilmesi [] |
Science Advances | A biomimetically hierarchical polyetherketoneketone scaffold for osteoporotic bone repair [33310848] |
J Bone Miner Res | Lgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/|??\catenin pathway [33950533] |
Br J Pharmacol | Andrographolide prevents bone loss via targeting ERRalpha‐regulated metabolic adaption of osteoclastogenesis [34233019] |
PHARMACEUTICAL BIOLOGY | Effects of icariin on the fracture healing in young and old rats and its mechanism [34511043] |
Evid Based Complement Alternat Med | Gujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1α/BNIP3 Pathway [34512780] |
Scandinavian Cardiovascular Journal | Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy [34296634] |
Chronobiol Int | Night shift work and osteoporosis-bone turnover markers among female blue-collar workers in Poland [Pubmed:35139709] |
Cell Metab | Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression [Pubmed:35235775] |
Cell Death Discov | BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis [Pubmed:35523787] |
Experimental and Molecular Medicine | Foxf2 represses bone formation via Wnt2b/β-catenin signaling [Pubmed:35668101] |
Bioactive Materials | Osteoporotic bone recovery by a bamboo-structured bioceramic with controlled release of hydroxyapatite nanoparticles [Pubmed:35386445] |
Journal of Orthopaedic Translation | Puerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathway [Pubmed:35228997] |
Journal of Orthopaedic Translation | Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35?… [] |
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