胱天蛋白酶1(CASP1)多克隆抗體
Polyclonal Antibody to Caspase 1 (CASP1)
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
- 編號PAB592Po01
- 物種Sus scrofa; Porcine (Pig,豬) 相同的名稱,不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 RPB592Po01-胱天蛋白酶1(CASP1)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性狀液體
- 濃度0.5mg/mL
- 且適物種Homo sapiens (Human,人)
- 應(yīng)用WB,IHC,ICC/IF
如果抗體需用于流式細(xì)胞術(shù),請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 720 ¥ 1680 ¥ 2400 ¥ 6000 ¥ 24000
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特異性
該抗體是針對CASP1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別CASP1。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunofluorescence: 5-30μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
編號 | 適用物種:Sus scrofa; Porcine (Pig,豬) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPB592Po01 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB592Po01 | 胱天蛋白酶1(CASP1)多克隆抗體 | WB,IHC,ICC/IF |
LAB592Po71 | 胱天蛋白酶1(CASP1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion [Pubmed:24816434] |
Fertil Steril | Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” [PubMed: 26474737] |
PLoS One | Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. [pubmed:28704412] |
Journal of?Virology | NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination [Pubmed:29386291] |
Journal of Translational Medicine | Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? [Pubmed:29665864] |
Reproductive?Sciences | A role for the inflammasome in spontaneous labor at term [Pubmed:27852921] |
Journal?of?Virology | CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES [Pubmed: 29386291] |
ACTA?Otorhinolaryngologica Italica | NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media [Pubmed: 30676848] |
American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women [Pubmed: 31148259] |
Taiwanese Journal of Obstetrics & Gynecology | Serum Caspase-1 levels in women with polycystic ovary syndrome [Pubmed: 32127139] |
Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients [] |
ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES [] | |
Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER [] |
LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation [34560082] |
Biol Reprod | The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice [34632484] |
J Mol Neurosci | TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury [Pubmed:35041191] |
Viruses | Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion [Pubmed:35062292] |
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