趨化因子C-X-C-基元受體4(CXCR4)單克隆抗體
Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4)
CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3
- 編號MAA940Hu22
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)D6
- Ig亞型 IgG2a Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPA940Hu01-趨化因子C-X-C-基元受體4(CXCR4)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 605 ¥ 1411 ¥ 2016 ¥ 5040 ¥ 20160
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Western Blot; Samples: Lane1: Jurkat cell lysate; Lane2: Human Platelet lysate;
Primary Ab: 0.3μg/ml Mouse Anti-Human CXCR4 Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對CXCR4的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別CXCR4。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA940Hu01 | 趨化因子C-X-C-基元受體4(CXCR4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA940Hu21 | 趨化因子C-X-C-基元受體4(CXCR4)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
| PAA940Hu08 | 趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA940Hu01 | 趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體 | WB; IHC; ICC; IP. |
| FAA940Hu01 | 抗趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體 | Flow cytometry. |
| FAA940Hu41 | 抗趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體(藻紅素標記) | Flow cytometry. |
| FAA940Hu51 | 抗趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體(別藻藍蛋白標記) | Flow cytometry. |
| FAA940Hu81 | 抗趨化因子C-X-C-基元受體4(CXCR4)多克隆抗體(異硫氰酸熒光素標記) | Flow cytometry. |
| MAA940Hu21 | 趨化因子C-X-C-基元受體4(CXCR4)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA940Hu22 | 趨化因子C-X-C-基元受體4(CXCR4)單克隆抗體 | WB; IHC; ICC; IP. |
| RAA940Hu21 | 趨化因子C-X-C-基元受體4(CXCR4)重組抗體 | WB; IF; ICC; IHC; IP; FCM. |
| SEA940Hu | 趨化因子C-X-C-基元受體4(CXCR4)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA940Hu | 趨化因子C-X-C-基元受體4(CXCR4)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| International Journal of Cancer | Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model [Wiley: source] |
| Plos one | Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma [PubMed: PMC3589458] |
| Atherosclerosis | The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: A randomized clinical trial [Pubmed:24530788] |
| Pharmacol Rep.? | Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression [Pubmed:25150002] |
| Pharmacological Reports | Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder [PubMed: 26481549] |
| Pharmacological Reports | A study of chemokines, chemokine receptors and interleukin-6 in patients with panic disorder, personality disorders and their co-morbidity [Pubmed:27208878] |
| BMC Cancer.? | Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists [pmc:PMC4866076] |
| Frontiers in Bioengineering and Biotechnology | Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison?… [Pubmed:29670878] |
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