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對氧磷酶1(PON1)多克隆抗體(生物素標(biāo)記)

Biotin-Linked Polyclonal Antibody to Paraoxonase 1 (PON1)

ESA; PON; Esterase A; Serum paraoxonase/arylesterase 1; Aromatic esterase 1; A-esterase 1; Serum aryldialkylphosphatase 1

  • 對氧磷酶1(PON1)多克隆抗體(生物素標(biāo)記) 產(chǎn)品包裝(模擬)
  • 對氧磷酶1(PON1)多克隆抗體(生物素標(biāo)記) 產(chǎn)品包裝(模擬)
  • Certificate 通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對PON1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別PON1。

用法

Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

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編號 適用物種：Homo sapiens (Human，人) 應(yīng)用(僅供研究使用，不用于臨床診斷！)
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參考文獻(xiàn)

雜志 參考文獻(xiàn)
Digestive Diseases and Sciences Fatty Liver Is Associated with Recurrent Bacterial Infections Independent of Metabolic Syndrome [PubMed: 20205513]
Clinica Chimica Acta Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome [PubMed: 21704607]
Journal of Laparoendoscopic & Advanced Surgical Techniques Combined Serum Proteomic and Metabonomic Profiling After Laparoscopic Sleeve Gastrectomy in Children and Adolescents [Wiley: source]
PLoS One. High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy [PubMed: 21887280]
Atherosclerosis Macrophage cholesterol efflux to plasma and HDL in subjects with low and high homocysteine levels: a FIELD substudy [PubMed: 21696738]
Lipids in Health and Disease Beneficial effects of omega-3 fatty acids in the proteome of high-density lipoprotein proteome [PubMed: PMC3480889]
British Journal of Nutrition Extra-virgin olive oil consumption reduces the age-related decrease in HDL and paraoxonase 1 anti-inflammatory activities [Pubmed: 23510814]
Diabetes & Metabolic Syndrome Paraoxonase 1: A better atherosclerotic risk predictor than HDL in type 2 diabetes mellitus [Pubmed: 23680251]
Redox Report Paraoxonase responses to exercise and niacin therapy in men with metabolic syndrome [Pubmed:25180827]
Toxicol Ind Health. Influence of α-tocopherol and α-lipoic acid on bisphenol-A-induced oxidative damage in liver and ovarian tissue of rats [Pubmed:25548375]
RETOS. Nuevas Tendencias en Educación Física, Deporte y Recreación A single session of aerobic exercise influences paraoxonase 1 activity and concentration [Articulo: 345738764042]
PLoS One Plasma Protein Biomarkers of Hepatocellular Carcinoma in HCV-Infected Alcoholic Patients with Cirrhosis [PubMed: 25789864]
Renal Failure Association of lipid profile with serum PON1 concentration in patients with chronic kidney disease [Pubmed:26888625]
Pharmacological reports The Role of PON-1, GR, IL-18, and oxLDL in Depression With and Without Posttraumatic Stress Disorder [science:article]
Clinical and Experimental Hypertension Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension [pubmed:27668323]
Diabetes & Metabolic Syndrome: Clinical Research & Reviews Paraoxonase-1 is a better indicator than HDL of Atherosclerosis-A pilot Study in North Indian population [pubmed:29254890]
Diabetes/Metabolism?Research?and Reviews A Case-control Study: The Association of Serum Paraoxonase 1 Activity and Concentration with the Development of Type 2 Diabetes Mellitus [pubmed:29156090]
Journal of Chromatography A Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis [S0021967317311858]
Pharmacological Reports The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder. [pubmed:28623707]
American Journal of Food Science and Health Palm Wine and Orijin Bitters Severed Hyperlipidemia and Immunomodulatory Responses in Atherogenic-diet Fed Male Wistar Rats [ISSN: 2381-7224]
Metabolic brain disease Individuals with autism have higher 8-Iso-PGF2α levels than controls, but no correlation with quantitative assay of Paraoxonase 1 serum levels [pubmed:28808839]
Therapeutic Apheresis And Dialysis Serum Endocan Levels are Associated With Paraoxonase 1 Concentration in Patients With Chronic Kidney Disease [Pubmed:29368426]
Biological?Trace?Element?Research Effect of Aqueous Extract of?Glycyrrhiza glabra?on the Biochemical Changes Induced by Cadmium Chloride in Rats [Pubmed: 30251228]
GLYCOCONJUGATE JOURNAL Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer [Pubmed: 30607521]
Hematology. Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails [Pubmed: 30661467]
Proteomics Clinical Applications Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy [Pubmed: 31162828]
Environment International Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures [Pubmed: 31639605]
Nutrition, Metabolism and Cardiovascular Diseases Phenotypes and concentration of PON1 in cardiovascular disease: the role of nutrient intake [Pubmed: 31757567]
Environment International Estimating renal and hepatic clearance rates of organophosphate esters in humans: Impacts of intrinsic metabolism and binding affinity with plasma proteins [Pubmed: 31783242]
RESPIRATORY RESEARCH The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation?… [Pubmed: 33148285]
CLINICAL RHEUMATOLOGY PON-1 haplotype (-108C> T, L55M, and Q192R) modulates the serum levels and activity PONase promoting an atherogenic lipid profile in rheumatoid arthritis patients [Pubmed: 32556934]
respiratory research The adverse alterations of HDL in quality promote septic ARDS via exacerbated pulmonary endothelial dysfunction []
J Transl Med Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans [33407555]
PLoS One Vitamin D status and systemic redox biomarkers in adults with obesity [30973911]
Oxid Med Cell Longev Repetitions of Strenuous Exercise Consistently Increase Paraoxonase 1 Concentration and Activity in Plasma of Average-Trained Men [34917230]
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