線粒體解偶聯(lián)蛋白1(UCP1)重組蛋白
Recombinant Uncoupling Protein 1, Mitochondrial (UCP1)
SLC25A7; UCP; Thermogenin; Solute carrier family 25 member 7
- 編號(hào)RPF557Mu01
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測(cè)分子量14.3kDa
- 實(shí)際分子量13kDa(差異分析請(qǐng)參閱說明書)
- 片段與標(biāo)簽Pro179~Leu296 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)7.7
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 1056 ¥ 2640 ¥ 5280 ¥ 15840 ¥ 39600
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPF557Mu02 | 線粒體解偶聯(lián)蛋白1(UCP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPF557Mu01 | 線粒體解偶聯(lián)蛋白1(UCP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAF557Mu01 | 線粒體解偶聯(lián)蛋白1(UCP1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAF557Mu02 | 線粒體解偶聯(lián)蛋白1(UCP1)多克隆抗體 | WB; IHC; ICC; IP. |
| LAF557Mu71 | 線粒體解偶聯(lián)蛋白1(UCP1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| LAF557Mu81 | 線粒體解偶聯(lián)蛋白1(UCP1)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| SEF557Mu | 線粒體解偶聯(lián)蛋白1(UCP1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMF557Mu | 線粒體解偶聯(lián)蛋白1(UCP1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Stem Cells | FM19G11 Favors Spinal Cord Injury Regeneration and Stem Cell Self-Renewal by Mitochondrial Uncoupling and Glucose Metabolism Induction [PubMed: 22865656] |
| Diabetes. | Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway [Pubmed:25249574] |
| Journal of Cachexia, Sarcopenia and Muscle | Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis [Doi: 10.1002] |
| FASEB J | Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis [PubMed: 26304220] |
| FASEB JOURNAL | Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and?… [Pubmed: 32954574] |
| Brown and beige adipose tissue regulate systemic metabolism to resist diet-induced obesity through metabolite signals in an inter-organ signaling axis [] | |
| Science reports | All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice [33627760] |
| Nature Communications | Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis [33772024] |
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