中性粒細(xì)胞彈性蛋白酶(NE)真核蛋白
Eukaryotic Neutrophil Elastase (NE)
ELANE; HLE; HNE; ELA2; PMN-E; Neutrophil Elastase; Medullasin; Polymorphonuclear Leukocyte Elastase; Bone Marrow Serine Protease; Leukocyte Elastase; PMN Elastase
- 編號EPA181Mu61
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源真核表達
- 宿主293F Cell
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞質(zhì), 細(xì)胞外基質(zhì)
- 預(yù)測分子量21.7kDa
- 實際分子量33kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ser27~Asn265 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點9.6
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 1555 ¥ 3888 ¥ 7776 ¥ 23328 ¥ 58320
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. Gene Sequencing (Extract)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APA181Mu61 | 中性粒細(xì)胞彈性蛋白酶(NE)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA181Mu01 | 中性粒細(xì)胞彈性蛋白酶(NE)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA181Mu02 | 中性粒細(xì)胞彈性蛋白酶(NE)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA181Mu61 | 中性粒細(xì)胞彈性蛋白酶(NE)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA181Mu01 | 中性粒細(xì)胞彈性蛋白酶(NE)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA181Mu02 | 中性粒細(xì)胞彈性蛋白酶(NE)多克隆抗體 | WB; IHC; ICC; IP. |
| SEA181Mu | 中性粒細(xì)胞彈性蛋白酶(NE)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA181Mu | 中性粒細(xì)胞彈性蛋白酶(NE)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Mediators of Inflammation | Long-Term Leukocyte Filtration Should Be Avoided during Extracorporeal Circulation [Hindawi: 612848] |
| Journal of Photochemistry and Photobiology B: Biology | A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins [Pubmed:25732262] |
| International Journal of Molecular Medicine | The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats [pubmed:27430552] |
| European?Journal?of?Trauma?and?Emergency | Xuebijing?injection?treatment?inhibits?vasopermeability?and?reduces?fluid?requirements?in acanine?burn?model. [pubmed:28070608] |
| Clin Exp Pharmacol Physiol. | Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide. [pubmed:28251688] |
| Journal of Cardiology | Targeted regulation of sympathetic activity in paraventricular nucleus reduces inducible ventricular arrhythmias in rats after myocardial infarction [10.1016:j.jjcc.2018.06.003] |
| Neuroscience | Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats [Pubmed:29684507] |
| Molecular and Cellular Biochemistry | Repetitive transcranial magnetic stimulation inhibits Sirt1/MAO-A signaling in the prefrontal cortex in a rat model of depression and cortex-derived astrocytes [Pubmed:28948423] |
| Neuropsychiatric disease and treatment | The depressive-like behaviors of chronic unpredictable mild stress-treated mice, ameliorated by Tibetan medicine Zuotai: involvement in the hypothalamic?… [Pubmed:29379286] |
| Behavioural?Brain?Research | Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats [Pubmed: 30423388] |
| Journal of?Pineal?Research | Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice [Pubmed: 30929267] |
| Fundamental & clinical pharmacology | Effect of antimicrobial peptides HNP‐1 and hBD‐1 on Staphylococcus aureus strains in vitro and in vivo [Pubmed: 31313350] |
| Cell Death & Disease | Erythromycin suppresses neutrophil extracellular traps in smoking-related chronic pulmonary inflammation [Pubmed: 31515489] |
| Journal of nutritional science and vitaminology | Co-Administration of Curcumin and Artepillin C Induces Development of Brown-Like Adipocytes in Association with Local Norepinephrine Production by Alternatively?… [Pubmed: 31474682] |
| Journal of Clinical Immunology | MiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes [Pubmed: 31749032] |
| Pathology & Oncology Research | Neutrophil Extracellular Traps Associate with Clinical Stages in Breast Cancer [Pubmed: 31656990] |
| Bioscience Reports | Inhibition of microRNA-146a attenuated heart failure in myocardial infarction rats [Pubmed: 31763669] |
| Oxidative Medicine and Cellular Longevity | Neutrophil Elastase Inhibitors Suppress Oxidative Stress in Lung during Liver Transplantation [Pubmed: 31871555] |
| Cytokine | Levels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis [Pubmed: 31927460] |
| Journal of neural transmission (Vienna, Austria : 1996) | Neurotransmitter system aberrations in patients with drug addiction [Pubmed: 32804296] |
| experimental eye research | Corneal epithelial injury-induced norepinephrine promotes Pseudomonas aeruginosa keratitis [Pubmed: 32376471] |
| CLINICAL AND EXPERIMENTAL HYPERTENSION | Hyperinsulinemia rather than insulin resistance itself induces blood pressure elevation in high fat diet-fed rats [Pubmed: 32349626] |
| Br J Pharmacol | Macrophage Extracellular Traps Aggravate Iron Overload?\Related Liver Ischemia/Reperfusion Injury [33959955] |
| Evidence-Based Complementary and Alternative Medicine | Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling??- [33505502] |
| Nat Sci Sleep | Depression of Non-Neuronal Cholinergic System May Play a Role in Co-Occurrence of Subjective Daytime Sleepiness and Hypertension in Patients with?… [34934375] |
| Neuromodulation: Technology at the Neural Interface | Transcutaneous Electrical Acustimulation Improved the Quality of Life in Patients With Diarrhea-Irritable Bowel Syndrome [Pubmed:35088760] |
| A Novel Role of Tinospora Cordifolia in Amelioration of Cancer-Induced Systemic Deterioration By Taming Neutrophil Infiltration and Hyperactivation [] |
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